According to Level 2 containment requirements, what is the minimum biosafety cabinet needed when there is a risk of aerosol production?

In a Level 2 containment setting, where there is a risk of aerosol production, the appropriate biosafety cabinet required is a Level 2 biosafety cabinet. This type of cabinet is specifically designed to protect both the laboratory personnel and the environment from exposure to infectious agents that can be transmitted through aerosols.

A Level 2 biosafety cabinet provides a barrier between the user and the biological material, utilizing HEPA filters to trap airborne particulates including pathogens. Additionally, it maintains a negative airflow to prevent contaminated air from escaping the cabinet. This level of containment is crucial when working with agents that are moderately hazardous and may cause infection through inhalation.

Using a Level 1 biosafety cabinet would not provide adequate protection because it lacks the necessary features to contain aerosols effectively. Furthermore, while a Level 3 biosafety cabinet offers a higher level of protection, it is excessive for agents classified as requiring Level 2 containment. A laminar flow hood, although useful in some laboratory settings, is not designed for work with infectious agents because it lacks the necessary containment features.

Thus, for handling materials where aerosol production poses a risk, the Level 2 biosafety cabinet is the most suitable choice to ensure safety and compliance with containment requirements.