Which result is most likely found in combination with a high serum creatinine result?

Study for the Medical Laboratory Professionals' Association of Ontario (MLPAO) Exam. Master the material with flashcards and multiple choice questions, with hints and explanations for each. Get ready for your exam!

High serum creatinine levels are typically associated with impaired kidney function, which leads to reduced clearance of waste products from the blood. In cases of kidney dysfunction, the kidneys are unable to effectively filter and excrete metabolites such as urea. As a result, urea, a nitrogenous waste product formed from protein metabolism, tends to accumulate in the bloodstream alongside elevated creatinine levels.

Both creatinine and urea levels are important indicators of renal function, and their elevations often occur together in conditions such as acute kidney injury or chronic kidney disease. Therefore, when serum creatinine is high, a concurrent high level of urea is the expected finding, reflecting the kidney's compromised ability to excrete waste.

The other options do not align with the physiological responses of the body to kidney dysfunction. A low urea level would likely indicate normal kidney function or a very low protein intake, which is not consistent with high creatinine. Normal urea levels would suggest that the kidney is functioning adequately, which is also inconsistent with high creatinine. A high chloride value does not directly relate to the kidney's capacity to excrete urea and creatinine, making it an unrelated finding in this context.

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